Hedy Lamarr

Tondelayo

Walter Pidgeon

Mr. Harry Witzel

Frank Morgan

The Doctor

Richard Carlson

Mr. Langford

Reginald Owen

Skipper of the Congo Queen

Henry O'Neill

The Reverend Dr. Roberts

Bramwell Fletcher

Wilbur Ashley

Clyde Cook

Ted, First Mate of the Congo Queen

Leigh Whipper

Jim Fish

Oscar Polk

Umeela

Darby Jones

Darby

Richard Ainley

Mr. Worthing

Jim Davis

Seaplane Pilot (uncredited)

John Burton

Jim Benson (uncredited)

Delos Jewkes

Native Singer (uncredited)

Martin Wilkins

Native Prisoner (uncredited)

Ed Allen

Native Drug Seller (uncredited)