Daniel Radcliffe

'Weird Al' Yankovic

Evan Rachel Wood

Madonna

Rainn Wilson

Dr. Demento

Toby Huss

Nick Yankovic

Jack Lancaster

Jim

Spencer Treat Clark

Steve

Tommy O'Brien

Bermuda

Arturo Castro

Pablo Escobar

Julianne Nicholson

Mary Yankovic

Diedrich Bader

Grizzled Narrator (voice)

Lin-Manuel Miranda

Doctor

Richard Aaron Anderson

Young Al

Thomas Lennon

Salesman

David Bloom

Teenage Al

Keanush Tafreshi

Kip

Andrew Steven Hernandez

Robbie

Paloma Esparza Rabinov

Hipster Teen

Scott Aukerman

Police Officer

Johnny Pemberton

Johnny Barf

Jonah Ray Rodrigues

Jonah Barf

Jeremy Bolm

Jeremy Barf

Eric Appel

Captain Buffoon (voice)

'Weird Al' Yankovic

Tony Scotti

Will Forte

Ben Scotti

Patton Oswalt

Heckler

Michael McKean

Sleazy MC

Dot-Marie Jones

Mama Bear

Dean Sharpe

Bartender

Jorma Taccone

Pee-Wee Herman

Demetri Martin

Tiny Tim

Paul F. Tompkins

Gallagher

Akiva Schaffer

Alice Cooper

Conan O'Brien

Andy Warhol

Emo Philips

Salvador Dali

Nina West

Divine

Jack Black

Wolfman Jack

David Dastmalchian

John Deacon

Anthony N.

Security Guard

Quinta Brunson

Oprah Winfrey

Julie Chang

Connie Chung

Josh Groban

Waiter

Seth Green

Radio DJ (voice)

Constantine Rousouli

Cone-Bra Dancer #1

James Brown III

Cone-Bra Dancer #2

Rocky Abou-Sakher

Terrorist Diner Patron

Chris Ryan

Kidnapper

Mike Escamilla

Guard #1

Chad Guerrero

Guard #2

Cesar Ramirez

Mariachi Band Member #1

Omar Estrada

Mariachi Band Member #2

Cesar Chavira

Mariachi Band Member #3

Jimmy Walker Jr.

Floor Manager

Trenyce

Diana Ross

James Preston Rogers

Hulk Hogan

William Guirola

Sicario

Paul Riley Fox

Elton John (uncredited)

Gordon Tarpley

David Bowie (uncredited)

Lisa Margaroli

Elvira, Mistress of the Dark (uncredited)

Erin O'Shea

Kate Pierson (uncredited)