Akio Ōtsuka

Solid Snake / Solidus Snake (voice)

田中英行

Hal 'Otacon' Emmerich (voice)

Takeshi Aono

Roy Campbell (voice)

沢木郁也

Ocelot (voice)

Takumi Yamazaki

Cyborg Ninja (voice)

Banjō Ginga

Liquid Snake (voice)

山本麻里安

Emma Emmerich (voice)

Kikuko Inoue

Rosemary (voice)

Shōzō Iizuka

Peter Stillman (voice)

Ryōtarō Okiayu

Vamp (voice)

Kenyu Horiuchi

Raiden (voice)

Yumi Tōma

Fortune (voice)

塩屋浩三

Fatman (voice)

阪脩

Sergei Gurlukovich (voice)

Daisuke Gouri

Scott Dolph (voice)

Kyoko Terase

Olga Gurlukovich (voice)

堀之紀

The Sorrow (voice)

藤本譲

President Johnson (voice)

Kikuko Inoue

Karen Hojo (voice)

小松里歌

Others (voice)

今村直樹

Others (voice)

平井啓二

Others (voice)

Keisuke Baba

Others (voice)

Takehiko Watanabe

Others (voice)

森岳志

Others (voice)

Takahiko Sakaguma

Others (voice)