John Turturro

Leon

Michael Badalucco

Charlie

Scott Glenn

Iggy

Jimmy Smits

Mike

Elizabeth Perkins

Susan

Amy Brenneman

Annie

JB Smoove

Chucky

Mike Starr

Larry

John Spencer

Ed

George DiCenzo

Jerry

Dayton Callie

Bernie

Saul Williams

Little Brother

Zachary Badalucco

Charlie's Son

Suzanne Costollos

Honey

Sybil Darrow

Pharmacist

Paul Diomede

Cheddar Fry

Mark Ethan

Gambler

Larry Fleischman

Dick

Hank Flynn

Uniform Cop

Ryan D. Gerber

Mikey

James Hanlon

Plain Clothes Cop

Steve Harris

Giant Black man who throws brick

Don Hewitt Sr.

Garbage Man

Colin Lane

Gray

Salem Ludwig

Uncle Paulie

Joshua Michael Lugo

Jerry's Son

Robert Miano

Sal

Adam Seth Nelson

Policeman

Jade Ostner

Child

Joe Paparone

Vinny

Angel Sing

Grocer

Steve Somers

Self

Jessica Romano

Baby Leon (uncredited)