Charles Hill Mailes

Mexican Jim

Claire McDowell

Mexican Jim's Wife

Blanche Sweet

Alice Hardy - the Prospector's Wife

W. Chrystie Miller

The Murdered Indian / Indian on Street

Robert Harron

The Murdered Indian's Son

Mae Marsh

A Murdered Settler (uncredited)

Alfred Paget

A Drunken Cutthroat / An Indian / Among Rescuers (uncredited)

Jack Pickford

An Indian (uncredited)

Charles Gorman

Jack Hardy - the Prospector

Frank Opperman

The Indian Chief / A Drunken Cutthroat / Bartender (uncredited)

Christy Cabanne

An Indian (uncredited)

William A. Carroll

In Bar / Among Rescuers (uncredited)

Frank Evans

In Bar / Among Rescuers (uncredited)

Bert Hendler

In Bar (uncredited)

Harry Hyde

Among Rescuers / Outside Pony Express Office (uncredited)

J. Jiquel Lanoe

An Indian / Among Rescuers (uncredited)

Wilfred Lucas

An Indian (uncredited)

W.C. Robinson

An Indian / In Bar / Among Rescuers (uncredited)

Charles West

Undetermined Role (uncredited)