Christian Slater

Floyd Lawton / Deadshot (voice)

Tara Strong

Harleen Quinzel / Harley Quinn (voice)

Billy Brown

Ben Turner / Bronze Tiger (voice)

Liam McIntyre

George Harness / Captain Boomerang (voice)

Vanessa Williams

Amanda Waller (voice)

Kristin Bauer

Crystal Frost / Killer Frost (voice)

Gideon Emery

Sameer Park / Copperhead (voice)

C. Thomas Howell

Eobard Thawne / Professor Zoom (voice)

Greg Grunberg

Steel Maxum (voice)

Julie Nathanson

Siobhan Smythe / Silver Banshee (voice) / Jewelee (voice)

Dave Fennoy

Blockbuster (voice) / Tobias Whale (voice) / Black Manta (voice)

Dania Ramirez

Scandal Savage (voice)

Cissy Jones

Knockout (voice) / Female Announcer (voice)

James Urbaniak

Lazlo Valentin / Professor Pyg (voice)

Jim Pirri

Vandal Savage (voice) / Werner Zytle / Count Vertigo (voice)

Natalie Lander

Darma (voice)

Trevor Devall

Punch (voice) / Thug #1 (voice)

David Boat

Harvey Dent / Two-Face (voice) / Thug #2 (voice)

Matthew Mercer

Savage Gunman / Argus Scientist / Belle Reve Doctor (voice)