John Hurt

Dr. Joe Buchanan / Narrator (voice)

Raúl Juliá

Dr. Victor Frankenstein

Nick Brimble

The Monster

Bridget Fonda

Mary Wollstonecraft Godwin

Jason Patric

Lord George Gordon Byron

Michael Hutchence

Percy Byshee Shelley

Catherine Rabett

Elizabeth Lavenza

Catherine Corman

Justine Moritz

William Geiger

Lab Technician

Mickey Knox

General Reade

Myriam Cyr

Information Officer

Terri Treas

Buchanan's Car (voice)

Cynthia Allison

Newswoman

Isabella Rocchietta

Dorrie

John Karlsen

Parson

Donald Hodson

Old Man