Cara Buono

Joanne

Isaach de Bankolé

Abraham

David Lansbury

Brian

Quinn Shephard

Linda

Robert Peters

Steve

Melissa Leo

Miriam

Paul Lazar

Larry

Helen Hanft

Shirley

Jimmy Gary Jr.

Sam

Rony Clanton

Frank

Sharon Wilkins

Jill

Joel de la Fuente

Alien

Robert Downey Sr.

Baker

Marcia Jean Kurtz

Brian's Mom

Larry Block

Brian's Dad

Lori Tan Chinn

Mrs. Kim

Jay Oakerson

Big Lab Assistant

Gregory Korostishevsky

Small Lab Assistant

Kristen Schaal

Information Librarian

Peter Bartlett

Curator

Laura Esterman

Psychiatrist

Susham Bedi

Vegetarian

Ed Wheeler

Guard

Jonah Meyerson

Henry

Richard M. Davidson

Doctor

David Smilow

Science Reporter

Michael Clinton

Farmer

Joseph McKenna

Confessor

Lori Braverman

Woman Gambler

Alberto Vasquez

Jerry

Tyagi Schwartz

Rosselli

Johann Carlo

Frieda

Ethan Crough

Jack

Kola Ogundiran

Peter

Sean Sutherland

Tourist

Peri Smilow

News Reporter

Dwandra Nickole

Admissions Person

Traci Parks

Conservator