Amy Adams

Charlotte (voice)

Elijah Wood

Adult Wilbur (voice)

Griffin Robert Faulkner

Young Wilbur (voice)

Jean Smart

Narrator (voice)

Cynthia Erivo

Goose (voice)

Natalie Chan

Fern (voice)

Danny Trejo

Gander (voice)

Randall Park

Templeton (voice)

Chris Diamantopoulos

Homer (voice)

Rosario Dawson

Edith (voice)

Ana Ortiz

Dolores (voice)

Tom Everett Scott

John (voice)

Leith M. Burke

George (voice)

Keith David

Old Sheep (voice)

Patricia Richardson

Widow Fussy (voice)

Dee Bradley Baker

Animals (voice)